I tested on several machines:
1. MacPro 2xXеоn, 32RAM
2. MacBookPro 15 Retina 8 Ram

in setup - “automatic”

In all machines, everything working fine except 4k with timeline fx. And I’ll repeat - inside connect FX the same FX working good.

You did test with color noise or real shot in 4k and don’t have troubles? Or why you asking about config?

Trouble that I can play 4k dpx 10bits in realtime without any troubles (macpro attached to quick storage), but can’t conform (((( ‘cause timeline FXs not working in my case.

I used 4k dpx 10bits and colornoise generated in project with default raster - 4k 10bit (16 for cg processing), in settings of project - legacy setup. I tested with geforce 650, 650m, 690. Today or tomorrow will have chance to try with quadro 4000. Versions of Smoke - 2013sp2 and 2013sp1, it was trial version, ‘cause we just testing new setup)

I used 4k as usually from film (super35 4k) - you have this preset in smoke. Tried again and this machine several minutes don’t answering))) I’ll check logs

from app log

[notice] 1997115776 EditdeskUI.C:1729 03/07/13:02:25:52.601 CLIPMGT : Create COL_NOISE from
[notice] 1997115776 menu.C:7211 03/07/13:02:25:52.601 POP MENU : GenerateNoiseDialog to Menus
[notice] 1997115776 menu.C:4160 03/07/13:02:25:54.593 BUTTON : [] SourceArea
[notice] 923799552 CoMsgLogger.cpp:211 03/07/13:02:25:56.842 Last entry repeated 1 more times.
[notice] 1997115776 ClipModel.C:517 03/07/13:02:25:56.842 CLIPMGT : Rename COL_NOISE to COL_NOISE
[notice] 1997115776 menu.C:4160 03/07/13:02:26:00.069 BUTTON : [] TimelineUICanvas
[notice] 923799552 CoMsgLogger.cpp:211 03/07/13:02:26:03.343 Last entry repeated 1 more times.
[notice] 1997115776 menu.C:4213 03/07/13:02:26:03.343 BUTTON : []
[notice] 1997115776 menu.C:4219 03/07/13:02:26:03.343 EditdeskTimelineUITabs(0)
[notice] 1997115776 menu.C:4213 03/07/13:02:26:04.539 BUTTON : []
[notice] 1997115776 menu.C:4219 03/07/13:02:26:04.539 EditdeskTimelineUITabs(1)
[notice] 1997115776 hotkeyItem.C:159 03/07/13:02:26:06.365 HOTKEY : [ED_GotoNextTrackTrx] [Next Transition (Current Track)]
[notice] 1997115776 menu.C:4160 03/07/13:02:26:08.878 BUTTON : [] TimelineUIPan
[notice] 1997115776 menu.C:4160 03/07/13:02:26:12.228 BUTTON : [] TimelineUICanvas
[notice] 1997115776 menu.C:4160 03/07/13:02:26:16.135 BUTTON : [] EffectsFxButton
[notice] 1997115776 hotkeyItem.C:159 03/07/13:02:26:21.912 HOTKEY : [ED_BigPlayerView] [Player View]
[notice] 1997115776 menu.C:4160 03/07/13:02:26:24.762 BUTTON : [] EffectsFxButton
[notice] 1997115776 menu.C:4155 03/07/13:02:26:26.544 BUTTON : [CC] CreateEffectCC(485)

------------------------------------

from shell log

Mar 07 02:24:53 :  Integrity check successful in 0.810118 sec
Mar 07 02:24:53 :  Unlocking volume stonefs7 ...
Mar 07 02:24:53 : MEMORY : Bytes available: 7068 MB
Mar 07 02:24:53 : MEMORY : Using 3000 MB (or 30 buffers of size 4096x3112 @ 10-bit).
Mar 07 02:24:53 : MEMORY : Allocated 3000 MB at address 0x201a8a000 using memalign()
Mar 07 02:24:56 :
Mar 07 02:24:56 : EDL Module: Portions Copyright 1991-1998 ALBA Editorial, Inc.,
Mar 07 02:24:56 :  All Rights Reserved.
Mar 07 02:24:56 :
Mar 07 02:25:37 : 2013-03-07 02:25:37.191 smoke[43898:1b07] -_continuousScroll is deprecated for NSScrollWheel. Please use -hasPreciseScrollingDeltas.
Mar 07 02:25:37 : 2013-03-07 02:25:37.194 smoke[43898:1b07] -deviceDeltaX is deprecated for NSScrollWheel. Please use -scrollingDeltaX.
Mar 07 02:25:37 : 2013-03-07 02:25:37.194 smoke[43898:1b07] -deviceDeltaY is deprecated for NSScrollWheel. Please use -scrollingDeltaY.